SILS-CNS consists of four groups within the Swammerdam Institute for Life Sciences of the University of Amsterdam, that work in the field of neuroscience and was established in 2005. The mission of SILS-CNS is to understand plasticity in the brain, in relation to epilepsy, stress and depression as well as cognition and emotion. The brain is studied in an integrated manner, from the level of the molecule, cell, network, all the way up to the organism.